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Trusted by 500k+ Customers Worldwide
TMG: Smarter Support for Healthy Fat Metabolism
Rho’s highly absorbable liposomal formula delivers trimethylglycine directly to your cells to promote healthy fat metabolism and lean muscle balance.
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GUARANTEED PURITY & SAFETY
THIRD-PARTY TESTED
HIGH ABSORPTION
Meet The Rho Partners
Trusted by Experts to support healthy body composition
Rho’s products are exactly what I need: bioavailable, clean, trusted ingredients, and easy to take
Laird Hamilton,
BIG WAVE SURFER, ENTREPRENEUR, Rho Partner
I've dedicated my career to improving the health and longevity of my patients. Rho is what I recommend and take personally as part of my holistic approach to health and longevity.
Dr. Amy Shah MD,
Cornell, Harvard & Columbia Trained MD
I was honestly blown away by how fast I felt the difference in my performance and recovery. Rho's supplements help me push harder in training and bounce back quicker than ever.
Noah Ohlsen,
11x CrossFit Games Athlete and 2x Medalist
Sustaining high performance is an inside-out job so I trust Rho's evidence-based formulas to support my energy, recovery and resilience.
Dr. Kristen Holmes,
Performance Scientist
These individuals partner with Rho Nutrition as paid ambassadors, sharing their real routines and results.
Rho’s products are exactly what I need: bioavailable, clean, trusted ingredients, and easy to take
Laird Hamilton,
BIG WAVE SURFER, ENTREPRENEUR, Rho Partner
I've dedicated my career to improving the health and longevity of my patients. Rho is what I recommend and take personally as part of my holistic approach to health and longevity.
Dr. Amy Shah MD,
Cornell, Harvard & Columbia Trained MD
Sustaining high performance is an inside-out job so I trust Rho's evidence-based formulas to support my energy, recovery and resilience.
Dr. Kristen Holmes,
Performance Scientist
Sustaining high performance is an inside-out job so I trust Rho's evidence-based formulas to support my energy, recovery and resilience.
Dr. Kristen Holmes,
Performance Scientist
These individuals partner with Rho Nutrition as paid ambassadors, sharing their real routines and results.
Training Hard But Still Not Losing Weight?
Fat loss isn't just about calories in versus calories out
Fat loss isn't just about calories in versus calories out
One of the key processes that regulates how your body burns fat and maintains lean muscle is methylation.
It helps maintain healthy insulin signaling, which determines whether your body efficiently burns fat or continues storing it.
And the key compound that supports this process is TMG (trimethylglycine).
When TMG levels are sufficient, it helps support efficient methylation and healthy metabolic function, including pathways involved in insulin signaling and body composition. When this support is lacking, these processes may not function as efficiently, which can impact how your body manages energy and maintains lean mass.*
Fat that won't budge despite a clean diet and consistent training
Losing weight on the scale but not changing shape
Lean muscle that's hard to build or maintain
A body composition plateau
You Don't Need Another Fat Burner. Your Body Needs More TMG
Most fat loss supplements rely on appetite suppression or high levels of stimulants. TMG does neither.
Rho Liposomal TMG delivers trimethylglycine in a highly absorbable liposomal form, directly supporting the pathways that govern fat loss and lean mass preservation.*
Get Liposomal TMG
This isn’t a weight loss hack. It’s a researched metabolic compound.
TMG is engineered to change how your body manages fat. Research shows that TMG significantly lowers body fat percentage and fat mass without altering your total body weight or BMI.
The result? A leaner, more efficient metabolism that prioritizes fat loss while supporting the maintenance of vital lean muscle.
Reference: https://pubmed.ncbi.nlm.nih.gov/31623137/
Support Fat Loss While Preserving Hard-Earned Lean Muscle
Supports Methylation & Healthy Homocysteine Levels
TMG acts as a methyl donor to support healthy homocysteine metabolism and the methylation pathways involved in energy production and overall metabolic balance.*
Supports Liver Function & Normal Fat Metabolism
TMG supports the methylation pathways that help your liver process and move fats normally, complementing a balanced diet and healthy lifestyle.*
Supports Performance, Recovery & Body Composition
When combined with regular exercise and adequate protein, TMG supports training quality, recovery, and a healthy body composition over time.*
Supports Everyday Metabolic Energy
TMG supports normal methylation activity, helping maintain healthy energy processes and overall metabolic wellbeing throughout the day.*
Supports Methylation & Healthy Homocysteine Levels
TMG acts as a methyl donor to support healthy homocysteine metabolism and the methylation pathways involved in energy production and overall metabolic balance.*
Supports Liver Function & Normal Fat Metabolism
TMG supports the methylation pathways that help your liver process and move fats normally, complementing a balanced diet and healthy lifestyle.*
Supports Performance, Recovery & Body Composition
When combined with regular exercise and adequate protein, TMG supports training quality, recovery, and a healthy body composition over time.*
Supports Everyday Metabolic Energy
TMG supports normal methylation activity, helping maintain healthy energy processes and overall metabolic wellbeing throughout the day.*
Try Liposomal TMG
Next Level of Cellular Absorption
Rho’s Liposomal Technology is designed to support efficient nutrient delivery, helping transport key compounds from ingestion to cellular uptake.
Supports Fat Metabolism
Step 1
Encapsulation
Trimethylglycine is enclosed in tiny, lipid-based spheres called liposomes. This helps shields it from digestive enzymes and stomach acids that normally break it down.
Step 2
Targeted Delivery
These liposomes help transport TMG safely through the digestive system, to support absorption in key tissues and where methylation is most active.
Step 3
Cellular absorption
By supporting absorption, your body is able to drive methylation reactions, recycle homocysteine, and support metabolic balance at the cellular level.
Try Liposomal TMG
THIRD-PARTY TESTED
Sugar, Gluten & Soy FREE
0 calories per serving
Made in a cGMP Facility
Verified Safe. Independently Tested.
Our liposomal TMG undergoes triple toxin screening by independent labs. Every batch meets strict safety and potency standards so you know exactly what’s in your supplement.
We screen for…
4 types of heavy metals
9 Microbial contaminants
16 different contaminants
Rho is Trusted by 500k Customers Worldwide
Solid Upgrade from Pills - TMG That Actually Tastes Good
I switched to Rho’s Liposomal TMG after years of choking down capsules. Honestly? The liquid form is a game-changer, no more dry-swallowing or stomach upset.
The orange-pineapple flavor is surprisingly nice, not too sweet, not artificial. I just take a quick teaspoon straight or mix it in water first thing in the morning. No weird aftertaste, and it goes down easy.
After about three weeks, I noticed steadier energy through the day, like my body was handling stress better, and my workouts felt smoother (less soreness, quicker bounce-back).
Hombre H.
Verified Buyer
What I like is it helps control my blood pressure along with other natural compounds. Like baha gold mineral salt hydration sour sop beet root exercise sunlight and stretching. If you have a chance I highly recommend RHO supplements because they deliver with results!
John R
Verified Buyer
Liposomal is the best!
My husband and I take this TMG and 5 other Rho products as a morning cocktail. So much better as a Liposomal than pills. Happy customer.
Jan T
Verified Buyer
Been feeling a great uptick in energy while working out and having been feeling stronger and less winded during lifts. TMG working great so far. Will definitely keep buying
Jeremy Binns
Verified Buyer
I've been taking TMG for a few weeks now. A focus of mine for this year is prioritizing health. I take along with a number of other Rho products and really feel great lately. Would recommend to friends and family.
James Devine
Verified Buyer
Questions? We have answers!
TMG (trimethylglycine), also known as betaine, is a naturally occurring compound found in foods such as beets, spinach, and whole grains. In the body, it acts as a methyl donor that helps recycle homocysteine back to methionine, supporting SAMe production and overall methylation activity.* TMG also functions as a cellular osmolyte, helping cells maintain normal fluid balance and resilience under metabolic and environmental stress.*
Liposomal TMG+ encapsulates TMG inside tiny phospholipid spheres that resemble cell membranes.* This delivery system is designed to help protect TMG through the digestive tract and support efficient absorption and cellular uptake, so more of what you take is available for use by your cells compared to standard non-liposomal forms.*
Liposomal TMG+ is designed for adults looking to support healthy homocysteine metabolism, methylation pathways, and liver function.* It can also be a useful addition for individuals focused on performance, recovery, and maintaining a healthy body composition, especially when combined with a nutrient-dense diet, regular exercise, and other foundational lifestyle habits.*
TMG helps support healthy homocysteine metabolism, and homocysteine is one factor involved in cardiovascular health.*
While TMG is not intended to diagnose, treat, cure, or prevent cardiovascular disease, supporting normal homocysteine metabolism is one way to help maintain overall cardiovascular function as part of a comprehensive lifestyle approach.*
Take 6 mL (just over one teaspoon) per day, or as recommended by your healthcare practitioner.* You may take it directly by mouth or mixed in a small amount of water or your favorite beverage. Each bottle contains 30 servings and will last 30 days when used as directed.*
Liposomal TMG+ can be taken at any time of day. Many people prefer taking it in the morning, with or without food, to support daytime methylation and energy pathways.* Others choose to split the serving between morning and early afternoon. The most important factor is consistent daily use as part of your routine.*
If you take prescription medications or have a medical condition, including cardiovascular, liver, or kidney conditions, talk with your healthcare provider before using Liposomal TMG+.* TMG is often used alongside B vitamins, creatine, and other metabolic support nutrients, but your clinician can help you determine the best combination for your individual needs.*
Yes. Liposomal TMG is designed to complement other Rho formulas, NAD+, glutathione, magnesium, curcumin + resveratrol, B12, and performance-support products.* If you are using multiple supplements or have a medical condition, consult your healthcare professional to personalize your protocol.*
TMG is generally well tolerated. Some individuals may notice mild digestive changes when starting TMG-containing supplements, especially at higher intakes.* If you are sensitive, consider starting with a smaller amount and gradually increasing to the full serving as tolerated. As always, speak with your clinician if you have specific concerns or if you experience persistent discomfort.*
Yes. All Rho products are manufactured in a non-GMO, gluten-free, soy-free, dairy-free, and nut-free facility. Every batch undergoes third-party testing for identity, purity, potency, and contaminants. All Rho products are produced in a cGMP-certified, FDA-registered facility with full quality documentation.
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